- Claude Bernard -
“The joy of discovery is certainly the liveliest that the mind of man can ever feel”
PUBLICATIONS
30. Kim, Y. C.; Yoon, H.; Na, Y.; Ghosh, R.; Jung, S.; Goh, Y. H.; Joo, S.; Jung, S.; Park, B. Y.; Yoo, T. H.; Park, S.; Doddareddy, M. R.; Wu, S.; Yun, H.* Integrated cascade biocatalysis of cannabigerolic acid through cyclodextrin-mediated stabilization and prenyltransferase engineering. Bioresour. Technol. 2025, 438, 133190.
29. Kim, J. H.; Yoon, H.-J.; Choi, Y.; Kim, J. S.; Ju, I. G.; Eo, H.; Lee, S.; Cho, J.-Y.; Park, B. Y.; Hong, S.-P.; Park, H.-J.; Oh, M. S.* 6-Shogaol, a neuro-nutraceutical derived from ginger, alleviates motor symptoms and depression-like behaviors and modulates the release of monoamine neurotransmitters in Parkinson's disease mice. Eur. J. Nutr. 2025, 64, 116.
28. Yu, C.; Ha, J.-K.; Park, M.; Lee, J.; Choi, J.; Park, B. Y.; Boyer, C.; Min, S. K.; Kwon, M. S.*
Rapid and precise synthesis of acrylic polymers driven by visible light, Chem. Sci., 2025, Advance Article.
27. Park, Y. S.; Kim, M.; Na, C. Y.; Ham, H. W.; Cho, J.-Y.; Park, B. Y.; Jung, C.; Park, D.; Yoo, T. H.*
A highly active and regioselective cannabigerolic acid synthase engineered from a promiscuous prenyltransferase NphB, Catal. Sci. Technol., 2025, Advance Article.
26 Hassan, A. H. E; Bae, E. S; Jeong, Y; Ock, C. W; El-Sayed, S. M; Kim, M; Radwan, M. F; Ibrahim, T. S; Cho, J. Y; Park, B. Y; Sim, J; Lee, S. K*; Lee, Y. S* Design, synthesis and evaluation of acetylcholine-antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6-Rb pathway in lung cancer. RSC Med. Chem., 2025, Advance Article
25 Park, J ; Kim, S ; Cho, J. Y ; Atriardi, S. R; Kim, J. Y; Mardhiyah, H; Park, B. Y*; Woo, S. K* Batch and flow synthesis of sulfides and sulfoxides using green solvents and oxidant through visible-light photocatalysis. Green Chem. 2025, 27, 3284 (‡ : equal contribution)
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24 Kim, J; Kim, J; Ju, I; Huh, E; Choi, Y; Lee, S; Cho, J. Y; Park, B. Y; Oh, M* Coadministration of 6-shogaol and Levodopa Alleviates Parkinson's Disease-Related Pathology in Mice. Biomol. Ther. 2024, 32(5), 523
23 Shin, H; Cho, J. Y; Park, B. Y*; Jung, C* Sulfur incorporation into nucleic acids accelerates enzymatic activity. Chem. Eng. J. 2024, 493, 152548
22 Kim, S; Suh, H; Park, B. Y* Photo-induced Multiphasic Reactions in Flow Process: A Decade of Progress. Asian. J. Org. Chem., 2023, 12, e202300484
21 Noh, J ; Cho, J. Y. ; Park, M; Park, B. Y* Visible-Light-Mediated TiO -Catalyzed Aerobic Dehydrogenation of N-Heterocycles in Batch and Flow. J. Org. Chem., 2023, 88, 15, 10682 (‡ : equal contribution)
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20 Kim, H., Lee, J.; Lee, S. J.; Oh, J. E.; Kim, S. D.; Malpani, Y. R.; Hwang, Y. J.; Park, B. Y.* Improving the sustainability and safety of ursodeoxycholic acid synthesis in continuous flow process with water Journal of Industrial and Engineering Chemistry. 2023, 119, 327.
19 Park, J. U.; Huang, L. Z.; Cho, H. J.; Park, B. Y.*; Kim, J. H.* One-Pot Synthesis of Unprotected 2-Acylpyrroles from 1,2,3-Triazoles and 2-Hydroxymethylallyl Carbonates Journal of Organic Chemistry. 2023, 88, 1, 585.
18 Park, J.; Lee, S.; Kim, G.; Malpani, Y. R.; Park, B.Y.; Hwang, Y.-J.* Flow Synthesis of L-α-Glycerylphosphorylcholine: Studies on Synthetic Routes Applicable to a Flow Reactor and Optimization of Reaction Conditions Pharmaceutics. 2022, 14, 2480.
17 Cho, J. Y.; Kim, H.; Oh, J. E.; Park, B. Y.* Recent advances in homogeneous/heterogeneous catalytic hydrogenation and dehydrogenation for potential liquid organic hydrogen carrier (Lohc) systems Catalysts. 2021, 11, 12, 1497.
16 Son, S. H.; Shin, J. W.; Won, H. J.; Yoo, H. S.; Cho, Y. Y.; Kim, S. L.; Jang, Y. H.; Park, B. Y.; Kim, N. J.* Synthesis of meta-(Indol-3-yl)phenols from Indoles and Cyclohexenone via Palladium(II)-Catalyzed Oxidative Heck Reaction and Dehydrogenative Aromatization in a One-Step Sequence Org. Lett., 2021, 23, 19, 7467.
11 Hassan, A. H. E., Yoo, S. Y., Lee, K. W., Yoon, Y. M., Ryu, H. W., Jeong, Y., Shin, J. S., Kang, S. Y., Kim, S. Y., Lee, H. H., Park, B. Y., Lee, K. T. & Lee, Y. S.* Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators European Journal of Medicinal Chemistry 2019, 180, 253.
10 Lee, H. H., Moon, Y. H., Shin, J. S., Lee, J. H., Kim, T. W., Jang, C., Park, C., Lee, J., Kim, Y., Kim, Y., Werz, O., Park, B. Y., Lee, J. Y. & Lee, K. T.* A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE2 in experimental models Prostaglandins and Other Lipid Mediators 2019, 144, 106347.
9 Yoo, H. S., Son, S. H., Cho, Y. Y., Lee, S. J., Jang, H. J., Kim, Y. M., Kim, D. H., Kim, N. Y., Park, B. Y., Lee, Y. S. & Kim, N. J.* Synthesis of Flavanones via Palladium(II)-Catalyzed One-Pot β-Arylation of Chromanones with Arylboronic Acids Journal of Organic Chemistry 2019, 84, 16, 10012.
14 Nam, S. B.; Khatun, N.; Kang, Y. W.; Park, B. Y.*; Woo, S. K.* Controllable one-pot synthesis for scaffold diversity via visible-light photoredox-catalyzed Giese reaction and further transformation Chem. Commun. 2020, 56, 2873.
13 Park, B. Y.; Pirnot. M. T.; Buchwald. S. L.* Visible Light-Mediated (Hetero)aryl Amination Using Ni(II) Salts and Photoredox Catalysis in Flow: A Synthesis of Tetracaine J. Org. Chem. 2020, 85, 3234. (cover art)
12 Kim, S. D.; Lee, J.; Kim, N-J.; Park, B. Y.* Visible-Light-Mediated Cross-Couplings and C-H Activation via Dual Photoredox/Transition-Metal Catalysis in Continuous-Flow Processes Asian J. Org. Chem. 2019, 8, 1578.
15 Kim, Y. M.; Yoo, H.-S.; Son, S. H.; Kim, G. Y.; Jang, H. J.; Kim, D. H.; Kim, S. D.; Park, B. Y.*; Kim, N.-J.* A Novel Approach to N‐Tf 2‐Aryl‐2,3‐Dihydroquinolin‐4(1H)‐ones via a Ligand‐Free Pd(II)‐Catalyzed Oxidative Aza‐Michael Cyclization Eur. J. Org. Chem. 2021, 4, 618.
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2018 and Before
8 Nguyen, K. D.; Park, B. Y.; Luong, T.; Sato, H.; Garza, V. J.; Krische, M. J.* Metal-Catalyzed Reductive Coupling of Olefin-Derived Nucleophiles: Reinventing Carbonyl Addition Science 2016, 354, 300.
7 Park, B. Y. ; Luong, T. ; Sato, H.; Krische, M. J.* Osmium(0) Catalyzed C-C Coupling of Ethylene and α-Olefins with Diols, Ketols or Hydroxy Esters via Transfer Hydrogenation J. Org. Chem. 2016, 81, 8585.
6 Park, B. Y.; Luong, T.; Sato, H.; Krische, M. J.* A Metallacycle Fragmentation Strategy for Vinyl Transfer from Enol Carboxylates to Secondary Alcohol C–H Bonds via Osmium- or Ruthenium-Catalyzed Transfer Hydrogenation J. Am. Chem. Soc. 2015, 137, 7652.
5 Park, B. Y.; Nguyen, K. D.; Chaulagain, M. R.; Komanduri, V.; Krische, M. J.* Alkynes as Allylmetal Equivalents in Redox-Triggered C–C Couplings to Primary Alcohols: (Z)- Homoallylic Alcohols via Ruthenium-Catalyzed Propargyl C–H Oxidative Addition J. Am. Chem. Soc. 2014, 136, 11902.
4 Park, B. Y.; Montgomery, T. P.; Garza, V. J.; Krische, M. J.* Ruthenium Catalyzed Hydrohydroxyalkylation of Isoprene with Heteroaromatic Secondary Alcohols: Isolation and Reversible Formation of the Putative Metallacycle Intermediate J. Am. Chem. Soc. 2013, 135, 16320.
3 Montgomery, T. P.; Hassan, A.; Park, B. Y.; Krische, M. J.* Enantioselective Conversion of Primary Alcohols to α-exo-Methylene-γ-Butyrolactones via Iridium-Catalyzed C–C Bond-Forming Transfer Hydrogenation: 2-(Alkoxycarbonyl)allylation J. Am. Chem. Soc. 2012, 134, 11100.
2 Park, B. Y.; Ryu, K. Y.; Park, J. H.; Lee, S.-g.* A dream combination for catalysis: highly reactive and recyclable scandium(III) triflatecatalyzed cyanosilylations of carbonyl compounds in an ionic liquid Green Chem. 2009, 11, 946.
1 Kim, J. H.; Park, B. Y.; Chen, S.-W.; Lee, S.-g.* In Situ Activation of a Latent Ruthenium–Carbene Complex in Ionic Liquid and Its Application in Ring-Closing Metathesis Eur. J. Org. Chem. 2009, 14, 2239.